Clinical Comparisons Of The Neurodegenerative Proteinopathies

Clinical Comparisons of the Neurodegenerative Proteinopathies Alzheimer’s disease and Chronic Traumatic Encephalopathy Alzheimer’s disease (AD) and chronic traumatic encephalopathy (CTE) are neurodegenerative diseases with overlapping biomarkers and behavioral symptoms, thus making the diagnosis of CTE difficult to fully address and identify. Additional concerns over the effects and correlation of multiple concussions are arising clinically as well as socially. Despite its recent attention and increasing recognition for further research, much remains unknown and unclear on the clinical and pathophysiology of CTE. Currently, CTE is only diagnosed and analyzed through pathological examinations performed post-mortem. Consequently due to†¦show more content†¦Alzheimer’s disease Alzheimer’s disease (AD) is a chronic, progressive type of amnesia, which causes severe memory loss and mental deterioration. It is common and typical for patients suffering from the various fluctuations and categories of amnesia to maintain intact, working, and procedural memory. The severity of the AD increases gradually over time, leading to complications and symptoms of such as confusion, depression, sleeplessness, and delusions. Although the primary onset of AD is old age, younger adults are also at risk. Late-onset Alzheimer’s disease affects the elderly and geriatric community. This influx of late-onset Alzheimer’s affects about 5% of people between the ages of 65 to 74 and almost 50% of people over 85 years old. Early-onset is another stage of this disease; occasionally affecting people younger than the age of 40. There is a negative genetic predisposition correlation for those whom suffer from early-onset dementia having family members related to be much more likely to develop AD, than those related to people with late-onset AD. Research of early-onset AD mainly focuses on genetic factors. Physiological research states genetics, environmental factors, or a combination of both cause AD. (Evans, George, 2000). During the course of going through the developmental stages of life and aging, the brain is subjected to numerous fluctuations. Several neurons as well